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Post by justaustin on Nov 30, 2008 16:27:16 GMT -5
Hi Chris and Lee, I apologize for the length. I've written about our 7year old son who appears to have Secondary AI. I am making plans to travel to Julie's doc in PA. I've been really slow with increasing his thyroid hormone replacement until his adrenals are better supported. Getting our labs copied. I've already been in email contact with him. I fired the endo and haven't heard back from our DO. forums.realthyroidhelp.com/viewtopic.php?f=12&t=6215 I had a phone consult our DO's PA last week and was pretty firm in my belief of the Secondary AI. I also discussed my concern for his low aldosterone, heat intolerance/even has head sweats at night(since toddler),low sodium..... Glucose(fasting) 72 (65-99) Sodium 136 (135-145) Potassium 4.4 Aldosterone 12.8 (4.0-76) for 4-7years Renin 4.62 (0.5-5.9) We restricted his sodium for 24hrs prior to testing, upright 2hrs. DHEA-S 83 <94 male age 7-8 Adrenal antibodies were negative in July. My concern is: he has body odor and has been requiring organic/aluminum free deodorant and I happened to notice some pubic hair(testicles) the other day. He is our only son. I don't know if this is normal. You both have experience with sons. I plan to check LH/FSH with next lab draw. Thanks, Laurie
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Post by chemom on Dec 1, 2008 10:03:31 GMT -5
My concern is: he has body odor and has been requiring organic/aluminum free deodorant and I happened to notice some pubic hair(testicles) the other day. He is our only son. I don't know if this is normal. You both have experience with sons. I plan to check LH/FSH with next lab draw. Thanks, Laurie Laurie, I only know from my two sons that are 13 and almost 11 (the littlest guy is only 5), but neither of them had these things going on so young. Sam didn't need deoderant til 12, and David doesn't need it yet. Have you had his IGF-1 tested yet? For some reason I thought you had, but it's Monday...
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Post by Chris Jackson on Dec 1, 2008 13:42:03 GMT -5
I haven't heard of pubic hair in a boy that young before. Rule out the possiblity he has been in direct and constant contact with someone using a testosterone patch. He could be producing it on his own. Get all his sex hormones tested, including LH and FSH.
Glucose may be high, but not sure what it should be with a child his age. His sodium suggests low aldosterone of course, but his potassium is higher than I would expect for secondary AI. I looked in my lab reference book to see what ranges for renin are for young kids, but only normal salt is listed and range for his age is similar to his renin range. If you use adult renin salt fast range of 3-24, then he would seem to have low renin. try to find other potassium tests. Sometimes I see people who have several, most will be low (or high) and ac couple of them will be high (or low).
I can't really commen on the DHEA-S. I don't know what it should be in kids.
Same with thyroid antibodies, adrenal antibodies need actual value.
You're welcome, Chris
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Post by justaustin on Dec 1, 2008 20:34:30 GMT -5
Lee,
You are right, we did have our son's IGF-1 tested. Varies between 120-130 within the last year (57-316). I'll have growth hormone checked along with IGF-1 with the next tests. He is on track with growth. He had xrays of his wrist/hand to determine bone age and he was spot on.
His ACTH was 19 (6-48) Am Cortisol ranges 8-10 (4.3-22.4)
Chris,
He takes Long Acting compounded T3. Wonder if he could have been cross contaminated via the compounding pharmacy? He's always required a much higher dose of T3 compared with T4. I'm waiting to hear back my our DO about changing our son to Armour as his T4 need has increased.I do not take any testosterone and neither does my husband.
So he needs: LH/FSH, individual sex hormones, IGF-1 with Growth Hormone. May need MRI? Anything else? I thought his adrenal antibodies were negative. I can't find them. Guess, will have to have those (re)checked.
I can't find a lab that gives actual #'s for Hashi's antibodies.
I've edited his glucose with the reference range.
Other Potassium tests: July 08 3.9 (3.5-5.2) April 08 4.2 (3.8-5.1) Dec 07 4.2 (3.8-5.1) July 07 4.2 (3.8-5.1)
Andrew receives 90-150mg of potassium via the bone and mineral supplement he takes. Would potassium appear skewed if one is dehydrated? He also has hypoparathyroidism. DO believes he has autoimmune polyendocrinopathy....
Thanks for all your input, Laurie
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Post by Chris Jackson on Dec 3, 2008 19:30:46 GMT -5
I never heard of compounding cross contaminating anything, but things like that do happen. Follow your gut instincts on this. If his testosterone tests show nothing, it's coming from somewhere.
I think those tests you listed cover it. Everyone found to be hypopit need an MRI. Can't be sure if tumor is present until MRI scan is done.
His potassium lean toward secondary AI. Potassium balances with sodium, so if sodium is low, dehydration can be present, but potassium is also affected by whether ACTH or Adrenals are the cause of AI.
You're welcome, Chris
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Post by Lethal Lee on Dec 6, 2008 20:57:24 GMT -5
Hi Laurie,
My twin sons didnt show pubic & underarm hair until early teens. At 16 they still dont have full muscle development and have sparse facial hair (shave once a week or so.
I suggest you get ALL Androgens & Sex hormones tested at same time •Androgens Panel (early 8am FASTING) includes Testosterone Free Testosterone (Bioavailable in USA) SHGB FAI DHEAS Androstenedione Dehydrotestosterone (DHT) *for males only
•Hormonal Panel includes FSH LH Estradiol (E2) *Men ask for ‘extra sensitive’ test for Males Estrone *available USA Estriol *available USA Progesterone LH/FSH Ratio
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Post by justaustin on Dec 6, 2008 23:00:18 GMT -5
Thanks Lee! Our son doesn't have any axilla hair. He's inherited my husband's dark italian skin and hair. My husband (only 1/2 Italian)gets a 5 o'clock shadow by noon. Hope you continue to feel better. Glad you had a nice birthday. Laurie
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