ginab
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Post by ginab on Nov 25, 2008 14:52:45 GMT -5
Hubby's labs are on RTH. forums.realthyroidhelp.com/viewtopic.php?f=11&t=10129I posted some of his labs on NTHAdrenals a while back. They said he may be hypopit. We think we found an endo that will do the appropriate tests, but the appointment is about 3 weeks away. I would love your input! Thank you! Gina
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Post by Chris Jackson on Nov 26, 2008 14:15:58 GMT -5
DHEA 3 (3-10) Suggests secondary AI DHEA-S = 136 (110-370 mcg/dL) Suggests secondary AI
Sodium = 140 (131-145 meq/L) Suspect salt wasting symptoms and low aldosterone Potassium = 4.2 (3.6-5.3 meq/L) 70% chance of low ACTH and low renin at this level.
HDL = 54 (40-199 mg/dL) Where HDL is low, sex hormones are usually low.
HR GTT Glucose, Fasting = 81 (65-99 mg/dL) Glucose, 1 hour = 142 (70-195 mg/dL) Glucose, 2 hour = 106 (70-140 mg/dL) Suggests low insulin
Insulin, Fasting = <2 (0-17 uIU/mL) For his GTT response, I wouldn't expect his insulin to be this low. For his insulin, I'd expect his GTT response to be a lot worse. I look for fasting insulin of close to 5, no higher than 10.
IGF-1 (Somatomedin-C) = 119 (106-225 ng/mL) I use old range of 150-350. His Igf-1 suggests his GH could be low. Get his GH tested.
I assume you posted his sex hormone tests with Phil? Your husband needs LH and FSH tested. Also should have ACTH and ACTH stim tests.
You're welcome, Chris
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ginab
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Post by ginab on Nov 26, 2008 15:10:50 GMT -5
When you say secondary AI, do you mean the pituitary isn't sending the right signal? I guess 'secondary to hypopit'? Just want to clarify!
Our GP doc put him on HGH shots. Not sure of the dose. He takes 1cc every other day of a 5.8mg/vial that is supposed to last about a month. (I did read your sticky on GH shots with anti-aging.) Does he need to be off of this 2 weeks for GH or ACTH stim testing? (I would assume, but just want to know for sure.)
GP also put him on 15 mg Cortef. (I know, not even close to enough!) He's going to have to wean so he can do the ACTH stim test. May have to wait until after the first of the year for endo appt so he can wean over Christmas break.
Doesn't insulin and GH kind of go together? One off can cause the other to be off, I think?
Do you think his cortisol 'lack of' rhythm indicates the secondary AI as well?
Actually, I don't know who Phil is! I guess I should post to his group too? I may find it before you get back to me, but in case I don't, please send me 'directions'. :-
It is the plan to do all the tests you suggested at the next doc visit. Well, all but the stim test.
You probably figured this out, but he's the dad of 2 of the 3 kiddo's of mine. (The other is adopted and is my biological nephew.) With me being hypothyroid (maybe Hashi's) and hypoadrenal and dad being hypopit, we certainly have messed up our kids! I say that mostly in jest, knowing that at least now we KNOW what is going on and can help them. I just hate it for them.
Thank you so much! Gina
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Post by Chris Jackson on Nov 27, 2008 19:42:52 GMT -5
Meaning secondary adrenal insufficient, low acth. Could actually be low CRH the cause. His doc should have tested and treated everything else, but no, HGH cures all. HGH will lower cortisol, so if possible he should be off the HGH and cortef for at least two weeks before testing. GH works with insulin and improves its sensitivity. If the DHEA tests were while he was on steroid, then I'm not able to give a firm opinion on if he is primary or secondary. The potassium is high enough, could match with primary.
Phil runs the mens forum at RTH and he's is having heart surgery, so don't know how long he will be away.
You're welcome, Chris
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ginab
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Post by ginab on Nov 29, 2008 1:31:48 GMT -5
What is CRH?
He was on no meds or supplements at the time of testing. He hated he couldn't take anything for 2 weeks!
No other tests were done, but this is an anti-aging doc. He's into HGH! Just trying something out, you know?
I think he's going to start weaning after he's done with his exams in 2 weeks. (He is a physics teacher, but is getting a second master's degree in health physics. Changing careers.) I think it will be the first of January before he will be able to do the ACTH stim test. Ugh. More waiting.
What did you mean by 'but no, HGH cures all'?
Your help is greatly appreciated. Gina
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Post by Chris Jackson on Dec 1, 2008 13:21:42 GMT -5
CRH is Corticotropin releasing hormone made in the hypothalamus and regulates ACTH in the pituitary.
No hormone therapy is a cure all, but many anti-aging docs think it is. See stickyon antiaging docs. Any doc can call himself antiaging, there is no medical degree for it. From what I've seen they don't know what they are doing with any of it. I've seen to many people get messed up by these docs, so I recommend staying away from them.
You're welcome, Chris
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ginab
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Posts: 47
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Post by ginab on Dec 1, 2008 18:43:10 GMT -5
The good thing about this doc is he thinks I'm smart! So, he actually goes along with what I told him I knew about AI and low thyroid. I think he will be more maleable than some other docs - including my Fibro doc! She just doesn't get it yet.
He was on board with all the things I needed and felt hubby needed an MRI at the very least to check his pituitary. We are hoping to get him into an endo to do the stim test soon.
Thank you again for your help. Gina
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Post by Chris Jackson on Dec 7, 2008 11:53:57 GMT -5
You're welcome, Chris
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