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Post by chorton28 on Jan 3, 2009 21:16:09 GMT -5
Hi Everyone, I am always thinking about how I can learn more about hypopit. and how I can improve things. I had these floating around in my head this week. These are some questions that I would love any suggestions or opinions on. Thank you
1. Why stress dose at once? Why not increase doses during the day?
2. Do vit. D levels effect how Armour gets in our cells? Or is that just Selenium and iron? Vit D just to reduce cancer risk?
3. Does malabsorption mean too little HC or too little thyroid?
4. Can these labs be a hypopit. person? With TSH so high? These labs are no hormones supplemented **** EXCEPT HC 20 mgs
TSH 16.0 (.450-4.5) Free T4 .46 (.61-1.76) RT3 43 (90-350) Free T3 1.6 (2.3-4.2)
Thank you again, Christine
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Post by fractal1 on Jan 4, 2009 2:43:06 GMT -5
Hi Christine, 1. Why stress dose at once? Why not increase doses during the day?You stress dose before the event. If you think you're going to have a stressful day, increase the dose for each time you take it. If you're going to do light exercise, stress dose before hand. ....Keeping in mind that different cortisol replacement have different half-lives. 2. Do vit. D levels effect how Armour gets in our cells? Or is that just Selenium and iron? Vit D just to reduce cancer risk?- Ferritin and B12 levels need to be high enough to ensure thyroid is adequately used - Selenium reduces thyroid antibodies - Impaired vitamin D supply is believed to contribute to the development of autoimmune processes & has lots of important functions: en.wikipedia.org/wiki/Vitamin_D3. Does malabsorption mean too little HC or too little thyroid?People could have problems absorbing either or both. 4. Can these labs be a hypopit. person? With TSH so high?
These labs are no hormones supplemented **** EXCEPT HC 20 mgs
TSH 16.0 (.450-4.5) Free T4 .46 (.61-1.76) RT3 43 (90-350) Free T3 1.6 (2.3-4.2)You only have to be deficient in one pituitary hormone to be hypopit. Isolated ACTH deficiency (i.e. secondary AI) often occurs with primary hypothyroidism, which this person has. To determine secondary AI, we need to see morning ACTH and cortisol without steroid replacement. Cheers
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Post by chorton28 on Jan 5, 2009 11:00:03 GMT -5
Thank you very much Ruth. On the last question. that is me and the previous saliva cortisol all times were low(depressed) CORTISOL LEVELS before any supplementation 8am 11 depressed (13-24) 12noon <1 depresed (5-10) 4pm <1 depressed (3-5) 12midnight <1 depressed (1-4)
ACTH plasma 33 ( 6-48) 2 weeks off pregnenlone, On nothing else
Prolactin 10.5 (2.8- 29.2)
LH 3.7 (1.9- 12.5) day 3 of cycle taken.
FSH 3.5 (2.5-10.2) day 3 of cycle. Thank you for your opinion. Appreciation, Christine
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Post by Lethal Lee on Jan 6, 2009 2:38:30 GMT -5
Hi Chris,
Fractal (Ruth) is away for two weeks so I will attempt the remaining questions.
First you asked "Does malabsorption mean too little HC or too little thyroid?" I think you meant IF you have Malabsorption is it due to low Cortisol or low Thyroid?
If so the anwer is really both as so are so closely interconnected. To explain if you have low cortisol then Thyroid hormone wont get to cells. If Thyroid is low and/or Cortisol is low then ALL of body systems are affected. That includes stomach/digestion Liver & intestine/bowels.
So if HC dosing is not right or Thyroid is not optimised then malabsorption to some degree is likely. Thats one reason why Hypos are so low in many vits & nutrients & need to supp them.
Add to that there is also age realated decline to consider. Low stomach acidity is common as we age. But I do wonder if so called age related decline is mostly Adrenal & other Endocrine issues that fail to be DXed & treated.
Lastly you asked whether you are likely Hypopit with Secondary AI.
TSH 16.0 (.450-4.5) Free T4 0.46 (.61-1.76) RT3 43 (90-350) Free T3 1.6 (2.3-4.2)
CORTISOL LEVELS (before any supplementation) 8am ........11 depressed (13-24) 12noon ..<1 depresed (5-10) 4pm........ <1 depressed (3-5) 12midnight <1 depressed (1-4)
ACTH plasma 33 ( 6-48) 2 weeks off pregnenlone, On nothing else
Prolactin 10.5 (2.8- 29.2)
LH 3.7 (1.9- 12.5) day 3 of cycle taken.
FSH 3.5 (2.5-10.2) day 3 of cycle.
Ouch on those Thyroid results. Clinically Hypothyroid of course as everythings outside range. Did you have Hashis Abs tested too? Obviously not Secondary Hypothyroid with that TSH.
Double ouch with those Saliva Cortisol results!!!! Deficient or non detectable Cortisol at all points. You must have felt terrible!!!!
The ACTH is not too bad but is NOT optimal. Optimal is high 40's low 50's. Having a ACTH Stim would have made it easier to definitely say that you are definitely Secondary AI. Did you test blood Cortisol at same time as the ACTH? What time was ACTH tested?
The LH & FSH while low in range may not necessarily indicate Secondary Hypogonadism. It depends on what the levels of Sex Hormones & Androgens were at the time tested. Blood tests prefered. & assuming not on any HRT for these.
Need Total & Free Testosterone SHBG DHEAS FAI Progesterone Estradiol LH FSH
Other things can provide clues. Low Potassium, low Renin is usually Secondary. Low Androgens are usually Secondary. Have you tested Aldosterone, Renin, Sodium & Potassium? What about Androgens & Sex Hormones pre Adrenal meds?
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Post by chorton28 on Jan 22, 2009 10:44:26 GMT -5
Soory Lee, I forgot about this post. I was posting other questions and got caught up and forgot. Thank you for your detailed response. Just one more question... If the pituitary can respond by giving a TSH like 16 in a range of .450-4.5 doesn't that say that maybe one is not hypopit. b/c it is reacting and giving out TSH to get the thyroid working. And it is the thyroid itself that has the problem I don't understand..If the pit. responds with TSH how can it be damaged in that area? Thanks, Christine
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Post by Chris Jackson on Jan 25, 2009 16:08:16 GMT -5
One high hormone does not rule out hypopit. In hashi's, youi can have high TSH and low acth. In acromegaly, you can have high GH and other pit hormones being low.
You're welcome, Chris
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